Deep-sleep brain waves linked to better blood sugar control

Scientists at the University of California, Berkeley, has made significant progress in understanding the link between sleep and diabetes. Their research suggests that deep-sleep brain waves play a crucial role in regulating the body’s sensitivity to insulin, leading to improved blood sugar control.

The researchers found that synchronized brain waves during deep sleep act as a trigger that sets off a chain reaction from the brain to the heart and ultimately affects the body’s regulation of blood sugar. Specifically, the combination of two brain waves known as sleep spindles and slow waves predicts an increase in insulin sensitivity, resulting in lower blood glucose levels.

This discovery is significant because sleep is a modifiable lifestyle factor, meaning that it can be improved and optimized. It opens the door to using sleep as part of a therapeutic approach to managing high blood sugar and Type 2 diabetes. The researchers believe that deep-sleep brain waves could serve as a sensitive marker for predicting next-day blood sugar levels, surpassing traditional sleep metrics in accuracy.

The study builds on previous research that demonstrated the role of deep-sleep brain waves in memory and learning. While those findings focused on rodents, this study reveals a similar mechanism in humans related to blood sugar management.

To investigate the link between deep-sleep brain waves and blood sugar control, the team analyzed sleep data from 600 individuals. They discovered that the coupling of these brain waves was a strong predictor of next-day glucose control, even after considering factors like age, gender, and sleep duration.

Further exploration led the researchers to uncover the underlying pathway connecting deep-sleep brain waves to blood sugar regulation. They found that stronger and more frequent coupling of these brain waves corresponded to a shift in the body’s nervous system state toward a more calming and relaxed state. This change, measured using heart rate variability, was associated with increased insulin sensitivity, allowing cells to absorb glucose from the bloodstream more effectively.

The findings were replicated in a separate group of 1,900 participants, increasing the confidence in the results.

The researchers emphasize the clinical significance of their findings. Current diabetes treatments and lifestyle changes can be challenging for patients to follow consistently. However, improving sleep quality may offer a painless and accessible approach to managing blood sugar levels. While sleep alone may not be a cure-all, the potential for technologies that can safely modulate deep-sleep brain waves holds promise for better blood sugar management and improved overall health.

Source: University of California – Berkeley

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